| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AFAP1L2 |
| Gene ID: | 84632 |
| Uniprot ID: | AF1L2_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AFAP1L2 (NP_001001936.1). |
| Immunogen Sequence: | MERYKALEQLLTELDDFLKI LDQENLSSTALVKKSCLAEL LRLYTKSSSSDEEYIYMNKV TINKQQNAESQGKAPEEQGL LPNGEPSQHSSAPQKSLPDL PPPKMIPERKQLAIPKTESP EGYYEEAEPYDTSLNEDGEA VSSSYESYDEEDGSKGKSAP YQWPSPEAGIELMRDARICA FLWRKKWLGQWAKQLCVIKD NRLLCYKSSKDHSPQLDVNL LGSSVIHKEKQVRKKEHKL |
| Tissue Specificity | Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas. |
| Post Translational Modifications | Tyrosine phosphorylated (by SRC). |
| Function | May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. |
| Protein Name | Actin Filament-Associated Protein 1-Like 2Afap1-Like Protein 2 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Actin Filament-Associated Protein 1-Like 2 antibodyAnti-Afap1-Like Protein 2 antibodyAnti-AFAP1L2 antibodyAnti-KIAA1914 antibodyAnti-XB130 antibody |
Information sourced from Uniprot.org