| Host: |
Alpaca |
| Applications: |
FC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Alpaca monoclonal nanobody anti-Beta-2 Adrenergic Receptor is suitable for use in Flow Cytometry research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
SAA1156 |
| Conjugation: |
Unconjugated |
| Isotype: |
VHH-8His-Cys-tag |
| Formulation: |
0.01M PBS, pH 7.4. |
| Purification: |
Purified by Nickel column. |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
| Protein Name | Beta-2 Adrenergic ReceptorBeta-2 AdrenoreceptorBeta-2 Adrenoceptor |
| Database Links | Reactome: R-HSA-390696Reactome: R-HSA-418555Reactome: R-HSA-5689880Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEarly EndosomeGolgi ApparatusColocalizes With Vhl At The Cell MembraneActivated Receptors Are Internalized Into Endosomes Prior To Their Degradation In LysosomesActivated Receptors Are Also Detected Within The Golgi Apparatus |
| Alternative Nanobody Names | Anti-Beta-2 Adrenergic Receptor nanobodyAnti-Beta-2 Adrenoreceptor nanobodyAnti-Beta-2 Adrenoceptor nanobodyAnti-ADRB2 nanobodyAnti-ADRB2R nanobodyAnti-B2AR nanobody |
Information sourced from Uniprot.org
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