Name: Anti-ADRA1A antibody (136-185 aa) (STJ91719)
SKU: STJ91719
Availability: InStock

Anti-ADRA1A antibody (136-185 aa) (STJ91719)

SKU:

STJ91719

$64.80 - $340.20

Host:	Rabbit
Applications:	WB/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Rabbit polyclonal antibody anti-Alpha-1A adrenergic receptor (136-185 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.

Clonality :	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IF 1:200-1:1000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ADRA1A
Gene ID:	148
Uniprot ID:	ADA1A_HUMAN
Immunogen Region:	136-185 aa
Specificity:	AR-Alpha 1A Polyclonal Antibody detects endogenous levels of AR-Alpha 1A protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human ADRA1A at the amino acid range 136-185

Post Translational Modifications	C-terminal Ser or Thr residues may be phosphorylated.
Function	This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.
Protein Name	Alpha-1a Adrenergic Receptor Alpha-1a Adrenoreceptor Alpha-1a Adrenoceptor Alpha-1c Adrenergic Receptor Alpha-Adrenergic Receptor 1c
Database Links	Reactome: R-HSA-390696 Reactome: R-HSA-416476 Reactome: R-HSA-416482
Cellular Localisation	Nucleus Membrane Multi-Pass Membrane Protein Cell Membrane Cytoplasm Membrane Caveola Location At The Nuclear Membrane Facilitates Heterooligomerization And Regulates Erk-Mediated Signaling In Cardiac Myocytes Colocalizes With Gnaq Plcb1 As Well As Lap2 At The Nuclear Membrane Of Cardiac Myocytes
Alternative Antibody Names	Anti-Alpha-1a Adrenergic Receptor antibody Anti-Alpha-1a Adrenoreceptor antibody Anti-Alpha-1a Adrenoceptor antibody Anti-Alpha-1c Adrenergic Receptor antibody Anti-Alpha-Adrenergic Receptor 1c antibody Anti-ADRA1A antibody Anti-ADRA1C antibody

Information sourced from Uniprot.org

Anti-ADRA1A antibody (136-185 aa) (STJ91719)

General Information

Model	Name	Host	Clonality	Reactivity	Application
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STJ92624	Anti-KRT10 antibody (136-185 aa) (STJ92624)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/IHC/IF/ELISA
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