Anti-ADCK4 antibody (1-90) (STJ117133)

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STJ117133
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COQ8B
Gene ID: 79934
Uniprot ID: COQ8B_HUMAN
Immunogen Region: 1-90
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human ADCK4 (NP_079152.3).
Immunogen Sequence: MWLKVGGLLRGTGGQLGQTV GWPCGALGPGPHRWGPCGGS WAQKFYQDGPGRGLGEEDIR RAREARPRKTPRPQLSDRSR ERKVPASRIS
Tissue Specificity Widely expressed, including renal podocytes.
Function Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration.
Protein Name Atypical Kinase Coq8b - Mitochondrial
Aarf Domain-Containing Protein Kinase 4
Coenzyme Q Protein 8b
Database Links Reactome: R-HSA-2142789
Cellular Localisation Mitochondrion Membrane
Single-Pass Membrane Protein
Cytoplasm
Cytosol
Cell Membrane
Alternative Antibody Names Anti-Atypical Kinase Coq8b - Mitochondrial antibody
Anti-Aarf Domain-Containing Protein Kinase 4 antibody
Anti-Coenzyme Q Protein 8b antibody
Anti-COQ8B antibody
Anti-ADCK4 antibody

Information sourced from Uniprot.org

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