| Tissue Specificity | Detected in blood plasma (at protein level). Widely expressed, with most abundant expression in human adult heart, lung, lymphoblasts, and placenta as well as fetal lung, liver, and kidney. In embryo, expressed in the outflow tract and atrium of the developing heart, the VII/VIII cranial nerve ganglion, and the notochord. |
| Function | Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity. |
| Protein Name | Adenosine Deaminase 2Cat Eye Syndrome Critical Region Protein 1 |
| Database Links | Reactome: R-HSA-5683826Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Adenosine Deaminase 2 antibodyAnti-Cat Eye Syndrome Critical Region Protein 1 antibodyAnti-ADA2 antibodyAnti-ADGF antibodyAnti-CECR1 antibodyAnti-IDGFL antibody |
Information sourced from Uniprot.org
