| Host: |
Rabbit |
| Applications: |
IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Acyl-Coenzyme A Synthetase Acsm1-Mitochondrial (150-250) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ACSM1 |
| Gene ID: |
116285 |
| Uniprot ID: |
ACSM1_HUMAN |
| Immunogen Region: |
150-250 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human ACSM1 (NP_443188.2). |
| Immunogen Sequence: |
ILYRLQLSKAKGIVTIDALA SEVDSIASQCPSLKTKLLVS DHSREGWLDFRSLVKSASPE HTCVKSKTLDPMVIFFTSGT TGFPKMAKHSHGLALQPSFP G |
| Function | Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids (e.g. butyric (C4) to decanoic (C10) acids), and certain carboxylate-containing xenobiotics, e.g. benzoate. Also catalyzes the activation of lipoate to lipoyl-nucleoside monophosphate. Activates lipoate with GTP at a 1000-fold higher rate than with ATP and activates both (R)- and (S)-lipoate to the respective lipoyl-GMP, with a preference for (R)-lipoate. |
| Protein Name | Acyl-Coenzyme A Synthetase Acsm1 - MitochondrialAcyl-Coa Synthetase Medium-Chain Family Member 1Benzoate--Coa LigaseButyrate--Coa Ligase 1Butyryl-Coenzyme A Synthetase 1Lipoate-Activating EnzymeMiddle-Chain Acyl-Coa Synthetase 1Xenobiotic/Medium-Chain Fatty Acid-Coa Ligase Hxm-B |
| Database Links | Reactome: R-HSA-177135Reactome: R-HSA-177162 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion |
| Alternative Antibody Names | Anti-Acyl-Coenzyme A Synthetase Acsm1 - Mitochondrial antibodyAnti-Acyl-Coa Synthetase Medium-Chain Family Member 1 antibodyAnti-Benzoate--Coa Ligase antibodyAnti-Butyrate--Coa Ligase 1 antibodyAnti-Butyryl-Coenzyme A Synthetase 1 antibodyAnti-Lipoate-Activating Enzyme antibodyAnti-Middle-Chain Acyl-Coa Synthetase 1 antibodyAnti-Xenobiotic/Medium-Chain Fatty Acid-Coa Ligase Hxm-B antibodyAnti-ACSM1 antibodyAnti-BUCS1 antibodyAnti-LAE antibodyAnti-MACS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
