Anti-ABCA5 antibody (1240-1320aa) (STJ190578)

SKU:
STJ190578

Current Stock:
Host: Rabbit
Applications: WB, ELISA
Reactivity: Human, Mouse, Rat
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Rabbit polyclonal antibody Anti-Cholesterol transporter (1240-1320aa) is suitable for use in Western Blot and ELISA.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Purification: ABCA5 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Concentration: 1 mg/ml
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABCA5
Gene ID: 23461
Uniprot ID: ABCA5_HUMAN
Immunogen Region: 1240-1320aa
Specificity: ABCA5 polyclonal antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from human ABCA5 protein.
Post Translational Modifications N-glycosylated.
Function Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport. May play a role in the processing of autolysosomes.
Protein Name Cholesterol Transporter Abca5
Atp-Binding Cassette Sub-Family A Member 5
Database Links Reactome: R-HSA-1369062
Cellular Localisation Golgi Apparatus Membrane
Multi-Pass Membrane Protein
Lysosome Membrane
Late Endosome Membrane
Cell Membrane
Localized At Cell Membrane Under High Cholesterol Levels
Alternative Antibody Names Anti-Cholesterol Transporter Abca5 antibody
Anti-Atp-Binding Cassette Sub-Family A Member 5 antibody
Anti-ABCA5 antibody
Anti-KIAA1888 antibody

Information sourced from Uniprot.org

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