||Human, Mouse, Rat
||FOR RESEARCH USE ONLY (RUO).
||Rabbit polyclonal antibody Anti-Cholesterol transporter (1240-1320aa) is suitable for use in Western Blot and ELISA.
||Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
||ABCA5 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
||WB 1:500-2000ELISA 1:5000-20000
||Store at-20°C, and avoid repeat freeze-thaw cycles.
||ABCA5 polyclonal antibody detects endogenous levels of protein.
||Synthesized peptide derived from human ABCA5 protein.
| Post Translational Modifications || N-glycosylated. |
| Function || Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport. May play a role in the processing of autolysosomes. |
| Protein Name || Cholesterol Transporter Abca5Atp-Binding Cassette Sub-Family A Member 5 |
| Database Links || Reactome: R-HSA-1369062 |
| Cellular Localisation || Golgi Apparatus MembraneMulti-Pass Membrane ProteinLysosome MembraneLate Endosome MembraneCell MembraneLocalized At Cell Membrane Under High Cholesterol Levels |
| Alternative Antibody Names || Anti-Cholesterol Transporter Abca5 antibodyAnti-Atp-Binding Cassette Sub-Family A Member 5 antibodyAnti-ABCA5 antibodyAnti-KIAA1888 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance