| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | S100 beta Blocking Peptide is synthetically produced from the Full length sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | S100P |
| Gene ID: | 6286 |
| Uniprot ID: | S100P_HUMAN |
| Immunogen Region: | Full length |
| Immunogen: | Full length protein of human S100 beta/beta homodimer. |
| Tissue Specificity | Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. |
| Function | May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE). |
| Peptide Name | Protein S100-P Migration-Inducing Gene 9 Protein Mig9 Protein S100-E S100 Calcium-Binding Protein P |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Nucleus Cytoplasm Cell Projection Microvillus Membrane Colocalizes With S100pbp In The Nucleus Colocolizes With Ezr In The Microvilli In A Calcium-Dependent Manner |
| Alternative Peptide Names | Protein S100-P protein Migration-Inducing Gene 9 Protein protein Mig9 protein Protein S100-E protein S100 Calcium-Binding Protein P protein S100P protein S100E protein |
Information sourced from Uniprot.org