| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
PBR Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
TSPO |
| Gene ID: |
706 |
| Uniprot ID: |
TSPO_HUMAN |
| Immunogen: |
Synthetic peptide corresponding to unique amino acid sequence on 18 kDa mitochondrial benzodiazepine receptor protein. |
| Tissue Specificity | Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids. |
| Function | Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides. |
| Peptide Name | Translocator ProteinMitochondrial Benzodiazepine ReceptorPkbsPeripheral-Type Benzodiazepine ReceptorPbr |
| Database Links | Reactome: R-HSA-196108 |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Translocator Protein proteinMitochondrial Benzodiazepine Receptor proteinPkbs proteinPeripheral-Type Benzodiazepine Receptor proteinPbr proteinTSPO proteinBZRP proteinMBR protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
