Mouse Reg3b protein (Recombinant) (N-GST & C-His) (STJP009187)

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STJP009187
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse Reg3b-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Reg3b
Gene ID: 18489
Uniprot ID: REG3B_MOUSE
Immunogen Region: Gly43-Gly175
Immunogen: Mus musculus (Mouse)
Post Translational Modifications Proteolytic processing by trypsin removes an inhibitory N-terminal propeptide and is essential for peptidoglycan binding and antibacterial activity.
Function Bactericidal C-type lectin which acts against several intestinal Gram-positive and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues. Acts as a hormone in response to different stimuli. Secreted by different cell types to activate its receptor EXTL3 and induce cell specific signaling pathways. In pancreas, is able stimulate cell proliferation.
Protein Name Regenerating Islet-Derived Protein 3-Beta
Reg-3-Beta
Pancreatitis-Associated Protein 1
Regenerating Islet-Derived Protein Iii-Beta
Reg Iii-Beta Cleaved Into - Regenerating Islet-Derived Protein 3-Beta 16.5 Kda Form - Regenerating Islet-Derived Protein 3-Beta 15 Kda Form
Database Links Reactome: R-MMU-6803157
Cellular Localisation Secreted
Found In The Apical Region Of Pancreatic Acinar Cells
Alternative Protein Names Regenerating Islet-Derived Protein 3-Beta protein
Reg-3-Beta protein
Pancreatitis-Associated Protein 1 protein
Regenerating Islet-Derived Protein Iii-Beta protein
Reg Iii-Beta Cleaved Into - Regenerating Islet-Derived Protein 3-Beta 16.5 Kda Form - Regenerating Islet-Derived Protein 3-Beta 15 Kda Form protein
Reg3b protein
Pap protein
Pap1 protein

Information sourced from Uniprot.org

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