Host: |
Goat/Goat |
Applications: |
ELISA |
Reactivity: |
Mouse |
Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: |
This MCP-1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
Clonality: |
Polyclonal/Polyclonal |
Conjugation: |
Unconjugated/Biotin |
Formulation: |
Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
Purification: |
Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
Concentration: |
0.5 mg/mL |
Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
Gene Symbol: |
Ccl2 |
Gene ID: |
20296 |
Uniprot ID: |
CCL2_MOUSE |
Immunogen: |
Capture immunogen: Recombinant Mouse MCP-1 protein.Detection Immunogen: Recombinant Mouse MCP-1 protein. |
Function | Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. Plays an important role in mediating peripheral nerve injury-induced neuropathic pain. Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B. |
Protein Name | C-C Motif Chemokine 2Monocyte Chemoattractant Protein 1Monocyte Chemotactic Protein 1Mcp-1Platelet-Derived Growth Factor-Inducible Protein JeSmall-Inducible Cytokine A2 |
Cellular Localisation | Secreted |
Alternative Antibody Pair Names | C-C Motif Chemokine 2 antibody pairMonocyte Chemoattractant Protein 1 antibody pairMonocyte Chemotactic Protein 1 antibody pairMcp-1 antibody pairPlatelet-Derived Growth Factor-Inducible Protein Je antibody pairSmall-Inducible Cytokine A2 antibody pairCcl2 antibody pairJe antibody pairMcp1 antibody pairScya2 antibody pair |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance