| Tissue Specificity | Ubiquitous. Most abundant in testis, adrenal, epididymis and heart. Low levels seen in the liver. |
| Post Translational Modifications | |
| Function | Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. |
| Protein Name | Beta-Hexosaminidase Subunit AlphaBeta-N-Acetylhexosaminidase Subunit AlphaHexosaminidase Subunit AN-Acetyl-Beta-Glucosaminidase Subunit Alpha |
| Database Links | Reactome: R-MMU-2022857Reactome: -MMU-2024101Reactome: -MMU-2160916Reactome: -MMU-9840310 |
| Cellular Localisation | Lysosome |
| Alternative ELISA Names | Beta-Hexosaminidase Subunit Alpha ELISA kitBeta-N-Acetylhexosaminidase Subunit Alpha ELISA kitHexosaminidase Subunit A ELISA kitN-Acetyl-Beta-Glucosaminidase Subunit Alpha ELISA kitHexa ELISA kit |
| output | |
Information sourced from Uniprot.org
