Name: Mouse GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015679)
SKU: STJE0015679
Availability: InStock

General Information
Product Properties
Target Information
Additional Info
Product Review

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.073ng/mL
Detection Limit:	0.156-10ng/mL
Short Description :	This GRIA4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids..

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Gria4
Gene ID:	14802
Uniprot ID:	GRIA4_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Palmitoylated. Depalmitoylated upon L-glutamate stimulation. ZDHHC3/GODZ specifically palmitoylates Cys-611, which leads to Golgi retention and decreased cell surface expression. In contrast, Cys-837 palmitoylation does not affect cell surface expression but regulates stimulation-dependent endocytosis. Phosphorylated at Ser-862 by PRKCG.phosphorylation increases plasma membrane-associated GRI4 expression.
Function	Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic acid, and kainic acid. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system and plays an important role in fast excitatory synaptic transmission. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse upon entry of monovalent and divalent cations such as sodium and calcium. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of L-glutamate.
Protein Name	Glutamate Receptor 4 Glur-4 Glur4 Ampa-Selective Glutamate Receptor 4 Glur-D Glutamate Receptor Ionotropic - Ampa 4 Glua4
Database Links	Reactome: R-MMU-399710 Reactome: -MMU-399719 Reactome: -MMU-416993 Reactome: -MMU-438066 Reactome: -MMU-8849932
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Postsynaptic Cell Membrane Cell Projection Dendrite
Alternative ELISA Names	Glutamate Receptor 4 ELISA kit Glur-4 ELISA kit Glur4 ELISA kit Ampa-Selective Glutamate Receptor 4 ELISA kit Glur-D ELISA kit Glutamate Receptor Ionotropic - Ampa 4 ELISA kit Glua4 ELISA kit Gria4 ELISA kit Glur4 ELISA kit
output

Information sourced from Uniprot.org

Model	Name	Reactivity	Application
STJE0015678	Human GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015678)	Human	ELISA
STJE0009298	Mouse GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4) Sandwich ELISA Kit Kit (STJE0009298)	Mouse	ELISA
STJE0009297	Human GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4) Sandwich ELISA Kit Kit (STJE0009297)	Human	ELISA
STJE0015677	Mouse GRIA3 (Glutamate Receptor, Ionotropic, AMPA 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015677)	Mouse	ELISA
STJE0015672	Mouse GRIA1 (Glutamate Receptor, Ionotropic, AMPA 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015672)	Mouse	ELISA

Mouse GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015679)

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