Post Translational Modifications | Likely to undergo an endoproteolytic process to form a four-cysteine-containing mature peptide with a canonical CXC chemokine scaffold after secretion. |
Function | Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. |
Protein Name | C-X-C Motif Chemokine 176-Cys Cxcl1713.6 Kda ProteinVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 |
Cellular Localisation | Secreted |
Alternative Protein Names | C-X-C Motif Chemokine 17 protein6-Cys Cxcl17 protein13.6 Kda Protein proteinVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 proteinCxcl17 proteinVcc1 protein |
Information sourced from Uniprot.org