Tissue Specificity | Expressed in all tissues examined (liver, kidney, spleen, thymus, brain and heart). Low levels in thymus. Also expressed in mononuclear cells, erythrocytes and platelets. Barely detected in neutrophils. |
Post Translational Modifications | |
Function | Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. |
Protein Name | Cd59a GlycoproteinMac-Inhibitory ProteinMac-IpMembrane Attack Complex Inhibition FactorMacifProtectinCd Antigen Cd59 |
Database Links | |
Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
Alternative ELISA Names | Cd59a Glycoprotein ELISA kitMac-Inhibitory Protein ELISA kitMac-Ip ELISA kitMembrane Attack Complex Inhibition Factor ELISA kitMacif ELISA kitProtectin ELISA kitCd Antigen Cd59 ELISA kitCd59a ELISA kitCd59 ELISA kit |
output | |
Information sourced from Uniprot.org