| Tissue Specificity | Detected in liver (at protein level). Highest expression in liver and T-cells. Also expressed in brain and lung. |
| Post Translational Modifications | N-glycosylated. |
| Function | Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine).the affinity for its substrates differs between isoforms created by alternative splicing. May play a role in classical or alternative activation of macrophages via its role in arginine transport. Isoform 1: Functions as a low-affinity, high capacity permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). Isoform 2: Functions as a permease that mediates the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). Shows a much higher affinity for L-arginine than isoform 1. |
| Protein Name | Cationic Amino Acid Transporter 2Cat-2Cat220.5Low Affinity Cationic Amino Acid Transporter 2Solute Carrier Family 7 Member 2T-Cell Early Activation ProteinTea |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Cationic Amino Acid Transporter 2 ELISA kitCat-2 ELISA kitCat2 ELISA kit20.5 ELISA kitLow Affinity Cationic Amino Acid Transporter 2 ELISA kitSolute Carrier Family 7 Member 2 ELISA kitT-Cell Early Activation Protein ELISA kitTea ELISA kitSlc7a2 ELISA kitAtrc2 ELISA kitTea ELISA kit |
| output | |
Information sourced from Uniprot.org
