| Tissue Specificity | Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues. |
| Function | Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6. |
| Peptide Name | Mitogen-Activated Protein Kinase Kinase Kinase 4Map Three Kinase 1Mapk/Erk Kinase Kinase 4Mek Kinase 4Mekk 4 |
| Cellular Localisation | CytoplasmPerinuclear RegionLocalized In Perinuclear Vesicular-Like StructuresProbably Golgi-Associated Vesicles |
| Alternative Peptide Names | Mitogen-Activated Protein Kinase Kinase Kinase 4 proteinMap Three Kinase 1 proteinMapk/Erk Kinase Kinase 4 proteinMek Kinase 4 proteinMekk 4 proteinMAP3K4 proteinKIAA0213 proteinMAPKKK4 proteinMEKK4 proteinMTK1 protein |
Information sourced from Uniprot.org
