| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
MAP3K4 Positive Control for STJ501674 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
MAP3K4 |
| Gene ID: |
4216 |
| Uniprot ID: |
M3K4_HUMAN |
| Specificity: |
This is positive control is recommended for use in combination with MAP3K4 antibody STJ501674. |
| Tissue Specificity | Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues. |
| Function | Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6. |
| Peptide Name | Mitogen-Activated Protein Kinase Kinase Kinase 4Map Three Kinase 1Mapk/Erk Kinase Kinase 4Mek Kinase 4Mekk 4 |
| Cellular Localisation | CytoplasmPerinuclear RegionLocalized In Perinuclear Vesicular-Like StructuresProbably Golgi-Associated Vesicles |
| Alternative Peptide Names | Mitogen-Activated Protein Kinase Kinase Kinase 4 proteinMap Three Kinase 1 proteinMapk/Erk Kinase Kinase 4 proteinMek Kinase 4 proteinMekk 4 proteinMAP3K4 proteinKIAA0213 proteinMAPKKK4 proteinMEKK4 proteinMTK1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
