Human VEGFD protein (Recombinant) (N-His) (STJP011337)

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STJP011337
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human VEGFD-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: VEGFD
Gene ID: 2277
Uniprot ID: VEGFD_HUMAN
Immunogen Region: Ser22-Pro354
Immunogen: Homo sapiens (Human)
Post Translational Modifications Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.
Function Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
Protein Name Vascular Endothelial Growth Factor D
Vegf-D
C-Fos-Induced Growth Factor
Figf
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-194313
Reactome: R-HSA-195399
Cellular Localisation Secreted
Alternative Protein Names Vascular Endothelial Growth Factor D protein
Vegf-D protein
C-Fos-Induced Growth Factor protein
Figf protein
VEGFD protein
FIGF protein

Information sourced from Uniprot.org

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