Human TPK1 protein (Recombinant) (N-His) (STJP007668)

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STJP007668
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TPK1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TPK1
Gene ID: 27010
Uniprot ID: TPK1_HUMAN
Immunogen Region: Met1-Ser243
Immunogen: Homo sapiens (Human)
Function Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP) utilizing UTP and therefore links the biosynthesis of TPP to pyrimidines metabolism. By producing thiamine pyrophosphate, a cofactor of the mitochondrial pyruvate dehydrogenase indirectly regulates pyruvate oxidation and lipogenesis. Although it can also catalyze thiamine phosphorylation using ATP and CTP in vitro, it does so with significantly lower efficiency and without physiological relevance evidence.
Protein Name Thiamine Pyrophosphokinase 1
Htpk1
Placental Protein 20
Pp20
Thiamin Pyrophosphokinase 1
Database Links Reactome: R-HSA-196819
Alternative Protein Names Thiamine Pyrophosphokinase 1 protein
Htpk1 protein
Placental Protein 20 protein
Pp20 protein
Thiamin Pyrophosphokinase 1 protein
TPK1 protein

Information sourced from Uniprot.org

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