| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | 1.Measured by its binding ability in a functional ELISA. Immobilized recombinant human BAFF at 5 Mu g/mL (100 Mu L/well) can bind recombinant human TNFRSF17 with a linear range of 3-20 ng/mL.|2.Loaded Human TNFRSF17/BCMA/CD269 Protein, C-hFc&His on P |
| Gene Symbol: | TNFRSF17 |
| Gene ID: | 608 |
| Uniprot ID: | TNR17_HUMAN |
| Immunogen Region: | Met1-Ala54 |
| Immunogen: | Recombinant Human TNFRSF17/BCMA/CD269 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ala54) of human TNFRSF17/BCMA/CD269 (Accession #NP_001183.2) fused with an Fc, 6×His tag at the C-terminu |
| Immunogen Sequence: | MLQMAGQCSQNEYFDSLLHA CIPCQLRCSSNTPPLTCQRY CNASVTNSVKGTNA |
| Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 17B-Cell Maturation ProteinCd Antigen Cd269 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane ProteinEndomembrane SystemPerinuclear Golgi-Like Structures |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 17 proteinB-Cell Maturation Protein proteinCd Antigen Cd269 proteinTNFRSF17 proteinBCM proteinBCMA protein |
Information sourced from Uniprot.org