Human RNH1 protein (Recombinant) (N-His) (STJP004058)

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STJP004058
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RNH1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RNH1
Gene ID: 6050
Uniprot ID: RINI_HUMAN
Immunogen Region: Asp218-Glu444
Immunogen: Homo sapiens (Human)
Function Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and angiogenin (ANG). May play a role in redox homeostasis. Required to inhibit the cytotoxic tRNA ribonuclease activity of ANG in the cytoplasm in absence of stress. Relocates to the nucleus in response to stress, relieving inhibition of ANG in the cytoplasm, and inhibiting the angiogenic activity of ANG in the nucleus.
Protein Name Ribonuclease Inhibitor
Placental Ribonuclease Inhibitor
Placental Rnase Inhibitor
Ribonuclease/Angiogenin Inhibitor 1
Rai
Cellular Localisation Cytoplasm
Nucleus
Localizes In The Cytoplasm In Absence Of Stress
Translocates To The Nucleus In Response To Stress
Alternative Protein Names Ribonuclease Inhibitor protein
Placental Ribonuclease Inhibitor protein
Placental Rnase Inhibitor protein
Ribonuclease/Angiogenin Inhibitor 1 protein
Rai protein
RNH1 protein
PRI protein
RNH protein

Information sourced from Uniprot.org

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