Human PLVAP protein (Recombinant) (N-His) (STJP006370)

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STJP006370
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PLVAP-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PLVAP
Gene ID: 83483
Uniprot ID: PLVAP_HUMAN
Immunogen Region: Arg123-Lys393
Immunogen: Homo sapiens (Human)
Function Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development.
Protein Name Plasmalemma Vesicle-Associated Protein
Fenestrated Endothelial-Linked Structure Protein
Plasmalemma Vesicle Protein 1
Pv-1
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Membrane
Caveola
Cytoplasm
Perinuclear Region
Membrane-Associated Protein Of Caveolae
Found In Fenestral And Stomatal Diaphragms In Fenestrated Endothelia And Transendothelial Channels
Also Colocalized With Cav1 In Perinuclear Region
Alternative Protein Names Plasmalemma Vesicle-Associated Protein protein
Fenestrated Endothelial-Linked Structure Protein protein
Plasmalemma Vesicle Protein 1 protein
Pv-1 protein
PLVAP protein
FELS protein
PV1 protein

Information sourced from Uniprot.org