Human PARVB protein (Recombinant) (N-His) (STJP008120)

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STJP008120
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PARVB-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PARVB
Gene ID: 29780
Uniprot ID: PARVB_HUMAN
Immunogen Region: His61-Glu364
Immunogen: Homo sapiens (Human)
Function Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.
Protein Name Beta-Parvin
Affixin
Database Links Reactome: R-HSA-446353
Reactome: R-HSA-446388
Cellular Localisation Cell Junction
Focal Adhesion
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cytoplasm
Cytoskeleton
Cell Projection
Lamellipodium
Myofibril
Sarcomere
Z Line
Constituent Of Focal Adhesions
Detected At The Tips Of The Leading Edge Of Cells
Colocalizes With F-Actin At The Tips Of Lamellipodia
Alternative Protein Names Beta-Parvin protein
Affixin protein
PARVB protein
CGI-56 protein

Information sourced from Uniprot.org