Human NR4A2 protein (Recombinant) (N-His) (STJP004743)

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STJP004743
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NR4A2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NR4A2
Gene ID: 4929
Uniprot ID: NR4A2_HUMAN
Immunogen Region: Met1-Thr335
Immunogen: Homo sapiens (Human)
Function Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.
Protein Name Nuclear Receptor Subfamily 4 Group A Member 2
Immediate-Early Response Protein Not
Orphan Nuclear Receptor Nurr1
Transcriptionally-Inducible Nuclear Receptor
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-4090294
Cellular Localisation Cytoplasm
Nucleus
Mostly Nuclear
Oxidative Stress Promotes Cytoplasmic Localization
Alternative Protein Names Nuclear Receptor Subfamily 4 Group A Member 2 protein
Immediate-Early Response Protein Not protein
Orphan Nuclear Receptor Nurr1 protein
Transcriptionally-Inducible Nuclear Receptor protein
NR4A2 protein
NOT protein
NURR1 protein
TINUR protein

Information sourced from Uniprot.org

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