Human NEO1 protein (Recombinant) (N-His) (STJP005797)

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STJP005797
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NEO1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NEO1
Gene ID: 4756
Uniprot ID: NEO1_HUMAN
Immunogen Region: Pro52-Ile426
Immunogen: Homo sapiens (Human)
Function Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response.
Protein Name Neogenin
Immunoglobulin Superfamily Dcc Subclass Member 2
Database Links Reactome: R-HSA-373752
Reactome: R-HSA-525793
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Neogenin protein
Immunoglobulin Superfamily Dcc Subclass Member 2 protein
NEO1 protein
IGDCC2 protein
NGN protein

Information sourced from Uniprot.org

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