Human NENF protein (Recombinant) (N-His) (STJP006207)

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STJP006207
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NENF-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NENF
Gene ID: 29937
Uniprot ID: NENF_HUMAN
Immunogen Region: Gly32-Phe172
Immunogen: Homo sapiens (Human)
Function Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance.
Protein Name Neudesin
Cell Immortalization-Related Protein 2
Neuron-Derived Neurotrophic Factor
Protein Gig47
Secreted Protein Of Unknown Function
Spuf Protein
Cellular Localisation Secreted
Extracellular Space
Mitochondrion
Endoplasmic Reticulum
Localized To Mitochondria And Endoplasmic Reticulum By Pink1 And Park7
Alternative Protein Names Neudesin protein
Cell Immortalization-Related Protein 2 protein
Neuron-Derived Neurotrophic Factor protein
Protein Gig47 protein
Secreted Protein Of Unknown Function protein
Spuf Protein protein
NENF protein
CIR2 protein
SPUF protein

Information sourced from Uniprot.org

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