Human NAP2 (Neutrophil Activating Protein 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017257)

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STJE0017257
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 10.1pg/mL
Detection Limit: 31.2-2000pg/mL
Short Description : This NAP2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: NAP1L4
Gene ID: 4676
Uniprot ID: NP1L4_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Ubiquitous. Biallelically expressed in fetal and adult tissues. Highest levels in testis.
Post Translational Modifications Phosphorylated at the G0/G1 boundary but it is not phosphorylated in S-phase. Phosphorylated protein remains in the cytoplasm in a complex with histones during the G0/G1 transition, whereas dephosphorylation triggers its transport into the nucleus at the G1/S-boundary. Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human.
Function Acts as a histone chaperone in nucleosome assembly.
Protein Name Nucleosome Assembly Protein 1-Like 4
Nucleosome Assembly Protein 2
Nap-2
Database Links
Cellular Localisation Nucleus
Cytoplasm
Present In The Cytoplasm And Excluded From The Nucleus During G0/G1 Phase
Then Relocates To The Nucleus By The Time Cells Are In S Phase
Phosphorylated Form Localizes In The Cytoplasm During The G0/G1 Transition
Whereas Dephosphorylation Leads To Relocalization Into The Nucleus At The G1/S-Boundary
Alternative ELISA Names Nucleosome Assembly Protein 1-Like 4 ELISA kit
Nucleosome Assembly Protein 2 ELISA kit
Nap-2 ELISA kit
NAP1L4 ELISA kit
NAP2 ELISA kit
output

Information sourced from Uniprot.org

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