| Host: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% Trehalose is added as protectant before lyophilisation. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/ug |
| Gene Symbol: | XCL1 |
| Gene ID: | 6375 |
| Uniprot ID: | XCL1_HUMAN |
| Immunogen Region: | Val22-Gly114 |
| Immunogen: | Recombinant Human Lymphotactin/XCL1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val22-Gly114) of Human Lymphotactin/XCL1 (Accession #NP_002986.1) fused with a His tag at the C-terminus. |
| Immunogen Sequence: | VGSEVSDKRTCVSLTTQRLP VSRIKTYTITEGSLRAVIFI TKRGLKVCADPQATWVRDVV RSMDRKSNTRNNMIQTKPTG TQQSTNTAVTLTG |
| Tissue Specificity | Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. |
| Function | Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment. |
| Protein Name | LymphotactinAtacC Motif Chemokine 1Cytokine Scm-1LymphotaxinScm-1-AlphaSmall-Inducible Cytokine C1Xc Chemokine Ligand 1 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Lymphotactin proteinAtac proteinC Motif Chemokine 1 proteinCytokine Scm-1 proteinLymphotaxin proteinScm-1-Alpha proteinSmall-Inducible Cytokine C1 proteinXc Chemokine Ligand 1 proteinXCL1 proteinLTN proteinSCYC1 protein |
Information sourced from Uniprot.org
