Tissue Specificity | Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver. Expressed in muscle, ligaments, periosteum, trabecular bone and throughout the cartilage, particularly in the growth plate and in articular chondrocytes. |
Post Translational Modifications | |
Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a role in the regulation of skeletogenesis, through a mechanism that involves integrin-mediated signaling and PTK2B/PYK2. |
Protein Name | Laminin Subunit Alpha-5Laminin-10 Subunit AlphaLaminin-11 Subunit AlphaLaminin-15 Subunit Alpha |
Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-6785807Reactome: R-HSA-8874081 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
Alternative ELISA Names | Laminin Subunit Alpha-5 ELISA kitLaminin-10 Subunit Alpha ELISA kitLaminin-11 Subunit Alpha ELISA kitLaminin-15 Subunit Alpha ELISA kitLAMA5 ELISA kitKIAA0533 ELISA kitKIAA1907 ELISA kit |
output | |
Information sourced from Uniprot.org