Tissue Specificity | |
Post Translational Modifications | |
Function | Cytokine that functions as an anti-inflammatory and proangiogenic factor. Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL13. Produced by osteocytes, stimulates granulopoiesis and neutrophil formation. Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3. |
Protein Name | Interleukin-19Il-19Melanoma Differentiation-Associated Protein-Like ProteinNg.1 |
Database Links | Reactome: R-HSA-8854691 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Interleukin-19 ELISA kitIl-19 ELISA kitMelanoma Differentiation-Associated Protein-Like Protein ELISA kitNg.1 ELISA kitIL19 ELISA kitZMDA1 ELISA kit |
output | |
Information sourced from Uniprot.org