Function | Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis. Required for proper regulation of SHH signaling. Plays an important role during spermatogenesis by modulating the assembly and elongation of the sperm flagella. |
Protein Name | Intraflagellar Transport Protein 81 HomologCarnitine Deficiency-Associated Protein Expressed In Ventricle 1Cdv-1 |
Database Links | Reactome: R-HSA-5620924 |
Cellular Localisation | Cell ProjectionCiliumCytoplasm |
Alternative Protein Names | Intraflagellar Transport Protein 81 Homolog proteinCarnitine Deficiency-Associated Protein Expressed In Ventricle 1 proteinCdv-1 proteinIFT81 proteinCDV1 protein |
Information sourced from Uniprot.org