Human H2AZ1 protein (Recombinant) (N-His) (STJP008913)

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STJP008913
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human H2AZ1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: H2AZ1
Gene ID: 3015
Uniprot ID: H2AZ_HUMAN
Immunogen Region: Ser19-Val128
Immunogen: Homo sapiens (Human)
Function Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
Protein Name Histone H2a.z
H2a/Z
Database Links Reactome: R-HSA-977225
Cellular Localisation Nucleus
Chromosome
Alternative Protein Names Histone H2a.z protein
H2a/Z protein
H2AZ1 protein
H2AFZ protein
H2AZ protein

Information sourced from Uniprot.org

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