Name: Human FKBP5 (FK506 Binding Protein 5) Sandwich ELISA Kit Kit (STJE0008934)
SKU: STJE0008934
Availability: InStock

Human FKBP5 (FK506 Binding Protein 5) Sandwich ELISA Kit Kit (STJE0008934)

SKU:

STJE0008934

$628.43 - $859.28

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General Information
Product Properties
Target Information
Additional Info
Product Review

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.061ng/mL
Detection Limit:	0.156-10ng/mL
Short Description :	This FKBP5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	FKBP5
Gene ID:	2289
Uniprot ID:	FKBP5_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Widely expressed, enriched in testis compared to other tissues.
Post Translational Modifications	Acetylation impairs ability to promote interaction between Akt/AKT1 and PHLPP1. Deacetylation by SIRT7 promotes interaction between Akt/AKT1 and PHLPP1, leading to suppress Akt/AKT1 activation. Ubiquitinated, leading to degradation in a proteasome-dependent manner. Deubiquitinated by USP49, leading to stabilization.
Function	Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1. Interacts with IKBKE and IKBKB which facilitates IKK complex assembly leading to increased IKBKE and IKBKB kinase activity, NF-kappa-B activation, and IFN production.
Protein Name	Peptidyl-Prolyl Cis-Trans Isomerase Fkbp5 Ppiase Fkbp5 51 Kda Fk506-Binding Protein 51 Kda Fkbp Fkbp-51 54 Kda Progesterone Receptor-Associated Immunophilin Androgen-Regulated Protein 6 Ff1 Antigen Fk506-Binding Protein 5 Fkbp-5 Fkbp54 P54 Hsp90-Binding Immunophilin Rotamase
Database Links	Reactome: R-HSA-3371497 Reactome: R-HSA-8939211 Reactome: R-HSA-9022699
Cellular Localisation	Cytoplasm Nucleus
Alternative ELISA Names	Peptidyl-Prolyl Cis-Trans Isomerase Fkbp5 ELISA kit Ppiase Fkbp5 ELISA kit 51 Kda Fk506-Binding Protein ELISA kit 51 Kda Fkbp ELISA kit Fkbp-51 ELISA kit 54 Kda Progesterone Receptor-Associated Immunophilin ELISA kit Androgen-Regulated Protein 6 ELISA kit Ff1 Antigen ELISA kit Fk506-Binding Protein 5 ELISA kit Fkbp-5 ELISA kit Fkbp54 ELISA kit P54 ELISA kit Hsp90-Binding Immunophilin ELISA kit Rotamase ELISA kit FKBP5 ELISA kit AIG6 ELISA kit FKBP51 ELISA kit
output

Information sourced from Uniprot.org

Model	Name	Reactivity	Application
STJE0015313	Human FKBP5 (FK506 Binding Protein 5) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015313)	Human	ELISA
STJE0008935	Human FKBPL (FK506 Binding Protein Like Protein) Sandwich ELISA Kit Kit (STJE0008935)	Human	ELISA
STJE0008932	Human FKBP1A (FK506 Binding Protein 1A) Sandwich ELISA Kit Kit (STJE0008932)	Human	ELISA
STJE0008933	Human FKBP4 (FK506 Binding Protein 4) Sandwich ELISA Kit Kit (STJE0008933)	Human	ELISA
STJE0015314	Human FKBPL (FK506 Binding Protein Like Protein) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015314)	Human	ELISA

Human FKBP5 (FK506 Binding Protein 5) Sandwich ELISA Kit Kit (STJE0008934)

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