Human FHL2 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007730)

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STJP007730
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FHL2-N-His-SUMO & C-Strep protein was developed from e. coli and has a target region of N-His-SUMO & C-Strep. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FHL2
Gene ID: 2274
Uniprot ID: FHL2_HUMAN
Immunogen Region: Gly16-Ser98
Immunogen: Homo sapiens (Human)
Function May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes.
Protein Name Four And A Half Lim Domains Protein 2
Fhl-2
Lim Domain Protein Dral
Skeletal Muscle Lim-Protein 3
Slim-3
Database Links Reactome: R-HSA-1989781
Cellular Localisation Cytoplasm
Nucleus
Myofibril
Sarcomere
Z Line
Alternative Protein Names Four And A Half Lim Domains Protein 2 protein
Fhl-2 protein
Lim Domain Protein Dral protein
Skeletal Muscle Lim-Protein 3 protein
Slim-3 protein
FHL2 protein
DRAL protein
SLIM3 protein

Information sourced from Uniprot.org