Human DYM protein (Recombinant) (N-His) (STJP005629)

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STJP005629
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DYM-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DYM
Gene ID: 54808
Uniprot ID: DYM_HUMAN
Immunogen Region: Ser546-Asp669
Immunogen: Homo sapiens (Human)
Post Translational Modifications Myristoylated in vitro.myristoylation is not essential for protein targeting to Golgi compartment.
Function Necessary for correct organization of Golgi apparatus. Involved in bone development.
Protein Name Dymeclin
Dyggve-Melchior-Clausen Syndrome Protein
Cellular Localisation Cytoplasm
Golgi Apparatus
Membrane
Lipid-Anchor
Sequence Analysis Programs Clearly Predict 1 Transmembrane Region
However
Pubmed:18996921 Shows That It Is Not A Stably Anchored Transmembrane Protein But It Weakly Associates With The Golgi Apparatus And Shuttles Between The Golgi And The Cytosol
Alternative Protein Names Dymeclin protein
Dyggve-Melchior-Clausen Syndrome Protein protein
DYM protein

Information sourced from Uniprot.org