Name: Human DVL1 protein (Recombinant) (N-His) (STJP003186)
SKU: STJP003186
Availability: InStock

Human DVL1 protein (Recombinant) (N-His) (STJP003186)

SKU:

STJP003186

€250.20 - €1,396.20

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Short Description :	Recombinant-Human DVL1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
Protein Name	Segment Polarity Protein Dishevelled Homolog Dvl-1 Dishevelled-1 Dsh Homolog 1
Database Links	Reactome: R-HSA-201681 Reactome: R-HSA-201688 Reactome: R-HSA-4086400 Reactome: R-HSA-4641258 Reactome: R-HSA-4641262 Reactome: R-HSA-5368598 Reactome: R-HSA-5663220 Reactome: R-HSA-9673324
Cellular Localisation	Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytosol Cytoplasmic Vesicle Localizes At The Cell Membrane Upon Interaction With Frizzled Family Members
Alternative Protein Names	Segment Polarity Protein Dishevelled Homolog Dvl-1 protein Dishevelled-1 protein Dsh Homolog 1 protein DVL1 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP008996	Human DVL1 protein (Recombinant) (N-His-SUMO) (STJP008996)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP015691	Human DVL1 protein (Recombinant) (N-GST & C-His) (STJP015691)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP007403	Human DVL1 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007403)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB

Human DVL1 protein (Recombinant) (N-His) (STJP003186)

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