Human DNAJC9 protein (Recombinant) (N-His) (STJP005770)

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STJP005770
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DNAJC9-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DNAJC9
Gene ID: 23234
Uniprot ID: DNJC9_HUMAN
Immunogen Region: Met1-Lys260
Immunogen: Homo sapiens (Human)
Function Acts as a dual histone chaperone and heat shock co-chaperone. As a histone chaperone, forms a co-chaperone complex with MCM2 and histone H3-H4 heterodimers.and may thereby assist MCM2 in histone H3-H4 heterodimer recognition and facilitate the assembly of histones into nucleosomes. May also act as a histone co-chaperone together with TONSL. May recruit histone chaperones ASF1A, NASP and SPT2 to histone H3-H4 heterodimers. Also plays a role as co-chaperone of the HSP70 family of molecular chaperone proteins, such as HSPA1A, HSPA1B and HSPA8. As a co-chaperone, may play a role in the recruitment of HSP70-type molecular chaperone machinery to histone H3-H4 substrates, thereby maintaining the histone structural integrity. Exhibits activity to assemble histones onto DNA in vitro.
Protein Name Dnaj Homolog Subfamily C Member 9
Hdjc9
Dnaj Protein Sb73
Cellular Localisation Nucleus
Cytoplasm
Cell Membrane
Predominantly Nuclear
Translocates To The Cytoplasm And Membrane After Heat Shock
Alternative Protein Names Dnaj Homolog Subfamily C Member 9 protein
Hdjc9 protein
Dnaj Protein Sb73 protein
DNAJC9 protein

Information sourced from Uniprot.org

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