| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CSPG5-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | CSPG5 |
| Gene ID: | 10675 |
| Uniprot ID: | CSPG5_HUMAN |
| Immunogen Region: | Ser361-Ser428 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | N-glycosylated. O-glycosylated.contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissue maturation. Phosphorylated.in intracellular and extracellular parts. |
| Function | May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. |
| Protein Name | Chondroitin Sulfate Proteoglycan 5Acidic Leucine-Rich Egf-Like Domain-Containing Brain ProteinNeuroglycan C |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-4420332 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynaptic Cell MembraneEndoplasmic Reticulum MembraneGolgi Apparatus MembraneCell SurfaceSecretedIn NeuronsLocalizes To Synaptic JunctionsAlso Detected In The Endoplasmic Reticulum And The GolgiPartially Enriched In Lipid Rafts |
| Alternative Protein Names | Chondroitin Sulfate Proteoglycan 5 proteinAcidic Leucine-Rich Egf-Like Domain-Containing Brain Protein proteinNeuroglycan C proteinCSPG5 proteinCALEB proteinNGC protein |
Information sourced from Uniprot.org