Post Translational Modifications | N-glycosylated. N-glycan at Asn-108: Hex5HexNAc4. |
Function | Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. |
Protein Name | Carboxypeptidase B2Carboxypeptidase UCpuPlasma Carboxypeptidase BPcpbThrombin-Activable Fibrinolysis InhibitorTafi |
Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-977606 |
Cellular Localisation | Secreted |
Alternative Protein Names | Carboxypeptidase B2 proteinCarboxypeptidase U proteinCpu proteinPlasma Carboxypeptidase B proteinPcpb proteinThrombin-Activable Fibrinolysis Inhibitor proteinTafi proteinCPB2 protein |
Information sourced from Uniprot.org