| Function | Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. Mediates threonyl dipeptide catabolism in a tissue-specific way. Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism. Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis. Plays a role in the regulation of cell cycle arrest and apoptosis. |
| Protein Name | Cytosolic Non-Specific DipeptidaseCndp Dipeptidase 2Glutamate Carboxypeptidase-Like Protein 1Peptidase AThreonyl Dipeptidase |
| Database Links | Reactome: R-HSA-174403Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Cytosolic Non-Specific Dipeptidase proteinCndp Dipeptidase 2 proteinGlutamate Carboxypeptidase-Like Protein 1 proteinPeptidase A proteinThreonyl Dipeptidase proteinCNDP2 proteinCN2 proteinCPGL proteinHEL-S-13 proteinPEPA protein |
Information sourced from Uniprot.org
