Human CD57/B3GAT1 protein (Recombinant) (N-His) (STJP006123)

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STJP006123
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD57/B3GAT1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: B3GAT1
Gene ID: 27087
Uniprot ID: B3GA1_HUMAN
Immunogen Region: His25-Ile334
Immunogen: Homo sapiens (Human)
Post Translational Modifications The soluble form derives from the membrane form by proteolytic processing.
Function Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
Protein Name Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1
Beta-1 -3-Glucuronyltransferase 1
Glucuronosyltransferase P
Glcat-P
Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase
Glcuat-P
Database Links Reactome: R-HSA-1971475
Cellular Localisation Isoform 1: Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Isoform 2: Golgi Apparatus Membrane
Endoplasmic Reticulum Membrane
Alternative Protein Names Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 protein
Beta-1 -3-Glucuronyltransferase 1 protein
Glucuronosyltransferase P protein
Glcat-P protein
Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase protein
Glcuat-P protein
B3GAT1 protein
GLCATP protein

Information sourced from Uniprot.org

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