Human CD16a (FcgR3a) protein (Recombinant) {Biotin} (STJP000193)

SKU:
STJP000193

Current Stock:
Host: HEK293
Applications: ELISA, WB
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Recombinant-Human CD16a (FcgR3a)-protein was developed from hek293. For use in research applications.
Conjugation: Biotin
Formulation: Recombinant CD16a is supplied as a 0.2 Mu m filtered PBS solution, pH7.2.
Dilution Range: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL.
Storage Instruction: Recombinant CD16a, as supplied, can be stored in working aliquots at 2-8°C for one month, or at-20°C to-70°C for twelve months. Avoid repeated freeze/thaw cycles.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: FCGR3A
Gene ID: 2214
Uniprot ID: FCG3A_HUMAN
Immunogen Region: ECD
Tissue Specificity Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
Post Translational Modifications Glycosylated. Contains high mannose- and complex-type oligosaccharides. Glycosylation at Asn-180 is mandatory for high affinity binding to the Fc and for discrimination between fucosylated and afucosylated IgG glycoforms. The soluble form is produced by a proteolytic cleavage.
Function Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-A
Cd16a Antigen
Fc-Gamma Riii-Alpha
Fc-Gamma Riii
Fc-Gamma Riiia
Fcriii
Fcriiia
Fcr-10
Igg Fc Receptor Iii-2
Cd Antigen Cd16a
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-9664323
Reactome: R-HSA-9664422
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Secreted
Exists Also As A Soluble Receptor
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-A antibody
Anti-Cd16a Antigen antibody
Anti-Fc-Gamma Riii-Alpha antibody
Anti-Fc-Gamma Riii antibody
Anti-Fc-Gamma Riiia antibody
Anti-Fcriii antibody
Anti-Fcriiia antibody
Anti-Fcr-10 antibody
Anti-Igg Fc Receptor Iii-2 antibody
Anti-Cd Antigen Cd16a antibody
Anti-FCGR3A antibody
Anti-CD16A antibody
Anti-FCG3 antibody
Anti-FCGR3 antibody
Anti-IGFR3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance