Human CCKBR/CCK2-R protein (Recombinant) (N-His) (STJP011426)

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STJP011426
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCKBR/CCK2-R-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CCKBR
Gene ID: 887
Uniprot ID: GASR_HUMAN
Immunogen Region: Arg243-Arg333
Immunogen: Homo sapiens (Human)
Function Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.
Protein Name Gastrin/Cholecystokinin Type B Receptor
Cck-B Receptor
Cck-Br
Cholecystokinin-2 Receptor
Cck2-R
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-881907
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Gastrin/Cholecystokinin Type B Receptor protein
Cck-B Receptor protein
Cck-Br protein
Cholecystokinin-2 Receptor protein
Cck2-R protein
CCKBR protein
CCKRB protein

Information sourced from Uniprot.org

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