Human CAPG protein (Recombinant) (N-His) (STJP007425)

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STJP007425
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CAPG-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CAPG
Gene ID: 822
Uniprot ID: CAPG_HUMAN
Immunogen Region: Met1-Lys348
Immunogen: Homo sapiens (Human)
Post Translational Modifications The N-terminus is blocked.
Function Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
Protein Name Macrophage-Capping Protein
Actin Regulatory Protein Cap-G
Cellular Localisation Nucleus
Cytoplasm
Melanosome
Cell Projection
Lamellipodium
Ruffle
In Macrophages
May Be Predominantly Cytoplasmic
Nuclear Localization Was Observed In Fibroblasts
Present At The Membrane-Cytoplasm Interface
In Activated Macrophages
Concentrated In The Ruffles Of The Leading Lamellipodia
Alternative Protein Names Macrophage-Capping Protein protein
Actin Regulatory Protein Cap-G protein
CAPG protein
AFCP protein
MCP protein

Information sourced from Uniprot.org

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