| Post Translational Modifications | Isoform 1 is phosphorylated on tyrosine residues during in vitro capacitation. Isoform 3 and isoform 5 are phosphorylated by GSK3B in vitro. Dephosphorylation affects its ability to bind calcium. |
| Function | May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium. |
| Protein Name | Calcium-Binding Tyrosine Phosphorylation-Regulated ProteinCalcium-Binding Protein 86Cancer/Testis Antigen 88Ct88Fibrousheathin IiFibrousheathin-2Fsp-2Testis-Specific Calcium-Binding Protein Cbp86 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionCiliumFlagellumLocalized To Fibrous Sheath Including The Surface Of The Longitudinal Columns And Ribs Of The Principal Piece Of Sperm FlagellaIsoform 1: NucleusIsoform 1Isoform 3 And Isoform 5 Are Both Nuclear And CytoplasmicIsoform 3: NucleusIsoform 5: Nucleus |
| Alternative Protein Names | Calcium-Binding Tyrosine Phosphorylation-Regulated Protein proteinCalcium-Binding Protein 86 proteinCancer/Testis Antigen 88 proteinCt88 proteinFibrousheathin Ii proteinFibrousheathin-2 proteinFsp-2 proteinTestis-Specific Calcium-Binding Protein Cbp86 proteinCABYR proteinCBP86 proteinFSP2 protein |
Information sourced from Uniprot.org
