Human BCO2 protein (Recombinant) (N-His) (STJP008105)

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STJP008105
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human BCO2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: BCO2
Gene ID: 83875
Uniprot ID: BCDO2_HUMAN
Immunogen Region: Ser69-Ile579
Immunogen: Homo sapiens (Human)
Function Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids. Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond. Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules.
Protein Name Carotenoid-Cleaving Dioxygenase - Mitochondrial
B-Diox-Ii
Beta -Beta-Carotene 9' -10'-Oxygenase
Beta-Carotene Dioxygenase 2
Database Links Reactome: R-HSA-975634
Cellular Localisation Mitochondrion
Alternative Protein Names Carotenoid-Cleaving Dioxygenase - Mitochondrial protein
B-Diox-Ii protein
Beta -Beta-Carotene 9' -10'-Oxygenase protein
Beta-Carotene Dioxygenase 2 protein
BCO2 protein
BCDO2 protein

Information sourced from Uniprot.org

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