| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human ATP6V1E1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | ATP6V1E1 |
| Gene ID: | 529 |
| Uniprot ID: | VATE1_HUMAN |
| Immunogen Region: | Met1-Asp226 |
| Immunogen: | Homo sapiens (Human) |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. |
| Protein Name | V-Type Proton Atpase Subunit E 1V-Atpase Subunit E 1V-Atpase 31 Kda SubunitP31Vacuolar Proton Pump Subunit E 1 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712Reactome: R-HSA-9857377 |
| Cellular Localisation | Apical Cell MembranePeripheral Membrane ProteinCytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneClathrin-Coated Vesicle Membrane |
| Alternative Protein Names | V-Type Proton Atpase Subunit E 1 proteinV-Atpase Subunit E 1 proteinV-Atpase 31 Kda Subunit proteinP31 proteinVacuolar Proton Pump Subunit E 1 proteinATP6V1E1 proteinATP6E proteinATP6E2 protein |
Information sourced from Uniprot.org
