| Tissue Specificity | |
| Post Translational Modifications | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD). |
| Function | Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation. Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium. In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels. |
| Protein Name | Arylsulfatase BAsbN-Acetylgalactosamine-4-SulfataseG4s |
| Database Links | Reactome: R-HSA-1663150Reactome: R-HSA-2024101Reactome: R-HSA-2206285Reactome: R-HSA-6798695Reactome: R-HSA-9840310 |
| Cellular Localisation | LysosomeCell Surface |
| Alternative ELISA Names | Arylsulfatase B ELISA kitAsb ELISA kitN-Acetylgalactosamine-4-Sulfatase ELISA kitG4s ELISA kitARSB ELISA kit |
| output | |
Information sourced from Uniprot.org
