Human ANO6 (Anoctamin 6) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013539)

Human ANO6 (Anoctamin 6) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013539)

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STJE0013539
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.127ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This ANO6 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: ANO6
Gene ID: 196527
Uniprot ID: ANO6_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed in embryonic stem cell, fetal liver, retina, chronic myologenous leukemia and intestinal cancer.
Post Translational Modifications
Function Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity.scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide. Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes. (Microbial infection) Upon SARS coronavirus-2/SARS-CoV-2 infection, is activated by spike protein which increases the amplitude of spontaneous Ca(2+) signals and is required for spike-mediated syncytia.
Protein Name Anoctamin-6
Small-Conductance Calcium-Activated Nonselective Cation Channel
Scan Channel
Transmembrane Protein 16f
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-6798695
Reactome: R-HSA-9733458
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Shows An Intracellular Localization
Alternative ELISA Names Anoctamin-6 ELISA kit
Small-Conductance Calcium-Activated Nonselective Cation Channel ELISA kit
Scan Channel ELISA kit
Transmembrane Protein 16f ELISA kit
ANO6 ELISA kit
TMEM16F ELISA kit
output

Information sourced from Uniprot.org

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