| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human AFM-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Gene Symbol: | AFM |
| Gene ID: | 173 |
| Uniprot ID: | AFAM_HUMAN |
| Immunogen Region: | Leu22-Asn599 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | N-glycosylated.more than 90% of the glycans are sialylated. |
| Function | Functions as a carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B. Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier. |
| Protein Name | AfaminAlpha-AlbuminAlpha-Alb |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Afamin proteinAlpha-Albumin proteinAlpha-Alb proteinAFM proteinALB2 proteinALBA protein |
Information sourced from Uniprot.org